Best Longevity & Anti-Aging Telehealth (2026): Graded & Ranked
Longevity and anti-aging telehealth has exploded — NAD+, peptides like sermorelin, rapamycin, metformin, GLP-1s, and full hormone-optimization memberships are a click away. We graded the providers that actually offer these protocols on what matters once the marketing fades: a transparent price, genuine clinical review, and real human support. CoreAge Rx earns our top spot for value — flat, doctor-reviewed protocols (NAD+ $93/mo, sermorelin $99/mo) with 503A compounding and included nurse and dietitian consults.
A necessary caveat. Most longevity interventions — NAD+, sermorelin and other GH-secretagogues, rapamycin and metformin for healthy adults — are clinically unproven to extend human lifespan. Only GLP-1 receptor agonists have hard cardiovascular-outcome trials behind them. This ranking grades provider quality, value, and transparency — it is not a claim that these therapies make you live longer. Read what the evidence actually shows before you start.
FTC disclosure
Disclosure: Some links on this site are affiliate or referral links. If you start a treatment or buy a product through them, we may earn a commission at no additional cost to you. Our rankings reflect published evidence and editorial judgment, not commissions. Read our full disclosure.
Specifically: CoreAge Rx is Longevity Graded's featured partner — if you start treatment through our link we may earn a commission, at no extra cost to you. The other providers below are shown for honest comparison only; we have no affiliate ties with them and do not link out to them. Our #1 pick reflects price, oversight, and support, not the commission.
Our #1 pick
$93–$99/mo flat
1
CoreAge Rx
Doctor-reviewed longevity peptides and NAD+ with flat, transparent pricing and built-in human support.
Featured partner · #1
Flat monthly — NAD+ $93/mo, Sermorelin $99/mo (no membership)
U.S.-licensed clinicians review an online intake; protocols (NAD+, sermorelin, a GLP-1 microdose, and a probiotic) are filled by a 503A compounding pharmacy. Every plan includes 1:1 consults with nurses and registered dietitians, an automatic refund if you are not approved, and flat transparent pricing with no separate membership or lab gate.
Strengths
Transparent flat pricing per protocol — NAD+ $93/mo, sermorelin $99/mo, no membership or lab surcharge
Doctor-reviewed protocols filled by a 503A compounding pharmacy
Included 1:1 support from nurses and registered dietitians
Automatic refund if you are not approved for treatment
Focused longevity menu (NAD+, sermorelin, GLP-1 microdose, probiotic) without lab-heavy onboarding
Trade-offs
Not a full hormone-optimization or comprehensive-lab clinic — by design
Like most longevity therapies, the protocols are compounded and not FDA-approved for anti-aging; the lifespan evidence is unproven (see our evidence review)
Start with CoreAge RxAutomatic refund if you are not approved · flat transparent pricing
The rest of the field
Real longevity and hormone-optimization telehealth providers, each checked live against their own site in 2026. We only state a price where the provider published a figure we could confirm; where pricing is membership-based or revealed only in the intake, we say so plainly.
2
AgelessRx
Broad longevity catalog (NAD+, metformin, sermorelin, GLP-1) with no required membership.
Pricing varies / per-treatment (no flat price published on site)
Online assessment reviewed by U.S.-licensed providers; prescriptions are filled through partnering pharmacies and shipped within 5–7 business days. The menu spans NAD+, metformin, low-dose naltrexone, glutathione, GLP-1 support, sermorelin, and a biological-age test. No membership is required to order.
Strengths
Wide longevity menu in one place (NAD+, metformin, LDN, sermorelin, GLP-1)
No mandatory membership — you can order individual treatments
Optional biological-age testing for those who want it
Trade-offs
No transparent flat price on the public site — totals are revealed in the intake and vary by treatment
Pharmacy network is described as 'partnering pharmacies' rather than a named 503A facility
Nurse / dietitian support is not part of the headline offer
Shown for honest comparison. We have no affiliate relationship with AgelessRx and do not link out to them. Verified on the provider's site: https://agelessrx.com
3
Hone Health
Hormone-optimization platform; longevity sits alongside TRT/HRT and is lab-gated.
At-home lab testing of 40+ biomarkers starts the program, followed by a telehealth physician consult and a personalized plan. Longevity is one track within a broader testosterone- and hormone-optimization platform; medication costs are separate from the membership fee.
Strengths
Comprehensive at-home biomarker panel for data-driven users
Both men's (TRT) and women's (HRT) hormone tracks
Low-cost basic membership tier for those who just want monitoring
Trade-offs
Lab-gated and membership-based — medication is billed on top of the monthly fee
Hormone/TRT framing; longevity peptides are not the core focus
More onboarding than a single flat-priced protocol
Shown for honest comparison. We have no affiliate relationship with Hone Health and do not link out to them. Verified on the provider's site: https://honehealth.com
4
Lifeforce
Premium, lab-heavy health-optimization membership with quarterly retesting.
$349 baseline assessment, then $129/mo membership; therapies extra
A phlebotomist-drawn at-home panel of 40–50+ biomarkers is interpreted by physicians, who build a program of nutraceuticals plus hormone and peptide therapies. Membership includes quarterly retesting and a health coach; recommended interventions are billed on top.
Strengths
Deep biomarker panel (40–50+ markers) with quarterly retesting
Personal health coach and physician-built protocol
Strong fit for users who want full data-driven optimization
Trade-offs
High entry cost: $349 baseline plus $129/mo before any therapy
Lab-heavy and membership-gated — the opposite of a flat per-protocol price
Recommended hormones/peptides/nutraceuticals are additional spend
Shown for honest comparison. We have no affiliate relationship with Lifeforce and do not link out to them. Verified on the provider's site: https://www.mylifeforce.com
Side by side
The honest comparison at a glance. “Flat pricing” means a single all-in figure with no separate membership, baseline assessment, or lab fee.
Provider
Price
Flat pricing
Consult incl.
Pharmacy
Labs required
Nurse/RD support
1.CoreAge RxFeatured
$93–$99/mo flat
Flat pricing: yes
Consult included: yes
503A
No
Nurse/RD support: yes
2.AgelessRx
Per-treatment
Flat pricing: no
Consult included: yes
Network
Optional
Nurse/RD support: no
3.Hone Health
$65 + $25–$155/mo
Flat pricing: no
Consult included: yes
Network
Yes
Nurse/RD support: yes
4.Lifeforce
$349 + $129/mo
Flat pricing: no
Consult included: yes
Network
Yes
Nurse/RD support: yes
Prices and program details were verified on each provider's own site in 2026 and can change without notice. “Optional” labs means the provider may offer or suggest testing but does not gate the basic plan on it; “Yes” means the program starts with required lab work. Confirm current terms with the provider before starting.
Why CoreAge Rx grades first
CoreAge wins on the fundamentals rather than on any claim that a peptide is a fountain of youth. Pricing is genuinely flat — NAD+ $93/month, sermorelin $99/month — with no membership or lab surcharge to discover later. The intake is reviewed by U.S.-licensed clinicians, protocols are filled by a 503A compounding pharmacy, and every plan includes 1:1 consults with nurses and registered dietitians. If you are not approved, you are refunded automatically.
We are equally honest about the science: outside of GLP-1 cardiovascular outcomes, the human lifespan evidence for these therapies is unproven, and compounded longevity protocols are not FDA-approved for anti-aging. This ranking is about provider quality, value, and experience — not a promise of a longer life. Read the full picture in our longevity-medicine evidence review before deciding.
We do not run sponsored reviews or accept payment to move a provider up the list. Grades weigh four factors, with price transparency carrying the most weight because hidden recurring fees — memberships, baseline assessments, lab panels — are the most common way longevity programs end up costing far more than they first appear.
Price transparency
We reward a single, all-in price you can see before you commit. Programs that stack a membership, baseline assessment, or lab fee on top of the therapy price rank lower than a true flat rate.
Clinical oversight
Real review by U.S.-licensed clinicians of an online intake, with a clear path to decline patients who are not appropriate candidates — not a rubber-stamp checkout.
Pharmacy quality
We note whether the compounding pharmacy is identified (e.g. a named 503A facility) rather than left vague as a 'partner network'.
Human support
Included access to nurses or registered dietitians — not just a shipped vial — meaningfully improves the experience and safety of any longevity protocol.
Read the evidence first
A provider ranking is only half the decision. Understand what longevity medicine can and cannot do before you start:
This page is informational and not medical advice. Longevity and anti-aging therapies are available by prescription after clinician review; most are compounded and not FDA-approved for anti-aging, and their effect on human lifespan is unproven. Talk to a licensed provider about whether any protocol is appropriate for you.