RxSpan MD Reviews: $249 Is the Month, $150 Is a Year

The one-sentence version

RxSpan MD publishes an all-inclusive price for NAD+ — consult, medication, supplies, shipping and support in one figure — and the month-to-month rate is $249, with $199, $166 and $150 available only on three-, six- and twelve-month plans. It is a physician-founded practice that names its founder — rare here — and it names all four of the pharmacies that may fill your prescription, with phone numbers — while never saying what kind of facility any of them is. It grades A, 13 out of 14; the missing point is the compounding standard it never states, and the grade is computed from published terms alone and cannot see who pays us.

What it is, and who it's for

RxSpan MD is a telehealth practice founded by Dr John Diaz, a board-certified plastic surgeon with more than twenty years in practice — Cornell, Albert Einstein College of Medicine, Alpha Omega Alpha, five years as president of the Society of Plastic Surgeons. His page frames the origin honestly: patients came for appearance and asked about weight and wellness, and the practice grew into "helping patients extend their healthspan through thoughtfully prescribed medications." Naming a clinician at all puts RxSpan ahead of most of this field — see what a longevity doctor actually is.

Its longevity catalog is wide: NAD+ by injection, nasal spray and flex-dose tablet, sermorelin ODT, glutathione, GHK-Cu, methylene blue, MIC B12, Lipo C and PT-141, beside a weight-loss line running from compounded semaglutide up to brand Wegovy at $1,349.

What it actually costs

All figures verified on rxspanmd.com on 26 July 2026, on the Longevity catalog.

The catalog. NAD+ Injection $249, NAD+ Nasal Spray $249, NAD+ Flex Dose Tablet $199, Sermorelin ODT $179, Glutathione $149, GHK-Cu $149, Lipo C $179, PT-141 $199, MIC B12 $129, Methylene Blue $99. Every single one of those numbers carries the same parenthetical beneath it: "(For the first month)."

The plan ladder behind it. Choosing a product opens a plan selector: Monthly $249/mo · 3-month plan $199/mo · 6-month plan $166/mo · 12-month plan $150/mo, with the three longer terms flagged "Max Saving." The overview beside it reads "Pre-paid monthly or quarterly," "Price includes consult, medication, supplies, shipping, and support," and "Cancel or change plans anytime."

So the honest summary is two sentences. $249 is a real, published, all-inclusive month-to-month price for NAD+ injection — better disclosed than most providers here, and the top of its range. Everything cheaper is a prepay, and the "(For the first month)" label means the catalog number is not by itself a monthly commitment either.

You pay before you are assessed. The checkout footer states: "After checkout, a provider will review your information to determine if treatment is right for you. Prescription is not guaranteed." The default plan selection totals $597 — three months at $199. That is the number a buyer who clicks through without changing anything is charged, not $249 and certainly not $150.

And there is no refund policy. RxSpan publishes four legal documents — Terms of Service, Privacy Policy, Notice of Privacy Practices and Medical Consent — and none is a refund or cancellation policy. What happens to your $597 if the provider declines you is not stated anywhere public. Ask before you check out; see also what longevity care costs.

What's included, what's extra

Included, per the site: the consult, the medication, supplies, expedited shipping, and "unlimited appointments, messaging and support" with "24/7 access to a dedicated team of specialists." Sitewide badges promise "No Hidden Fees" and "Doctor-led Plans & Coaching."

Not offered: bloodwork, biomarker panels or any before-and-after testing. Nothing here measures whether the protocol did anything — the same structural gap most of this category has, and the reason longevity biomarker panels sit outside it.

Clinical oversight and the pharmacy

Oversight is genuinely above average on the disclosure axis: a named, credentialled founding physician, unlimited clinician access inside the price, and an explicit statement that a prescription is not guaranteed.

A correction, and it reverses what this page used to say. An earlier version of this review stated that RxSpan "says nothing whatsoever about the pharmacy that fills your prescription." That was wrong, and it was wrong because we read the Terms and the rendered page and stopped there. RxSpan's FAQ is client-hydrated — the answers are fetched after the page loads, so they are invisible to anything that reads the served HTML.

Fetched from the endpoint the page itself loads (intake.rxspanmd.com/api/getOrgData), the answer to "Who are your Pharmacy Providers?" names four, each with a dialable number: Belmar Pharmacy (800-525-9473), Strive Pharmacy (855-405-5993), Epiq Scripts (833-654-3553) and Casa Pharma Rx (877-937-6868). The same source names the clinical team — Lion MD, with Dr Ana Lisa Carr, MD and Dr Kelly Tenbrink, MD, both with published NPI numbers. On disclosure, that puts RxSpan ahead of most providers here rather than behind it.

Two caveats belong beside it, and they are the reason this is the middle rung and not the top. It classifies none of them. No Section 503A claim, no 503B claim, no compounding standard of any kind appears on the site or in the data its FAQ loads from — so you know who may fill the prescription and not to what standard. And the disclosure is real but not exclusive: the identical four are published by Care Bare Rx, Synergy Rx, Breeze Meds and Sunlight, all running on the same CareValidate backend. It is one shared bench, not four independent attestations. Naming without classifying is the middle rung of our rubric — one point of two, and the only point this row drops.

One thing travels with the name. Belmar, one of the four, received an FDA warning letter addressed to Belmar Pharma Solutions, Drug Depot, LLC., dba APS Pharmacy in March 2023, and the FDA closed it out in October 2023 — so there is no open letter against the pharmacy. RxSpan MD itself holds no FDA warning letter — a live index search for "rxspan", "rxspan md" and "care360", its platform vendor, returned no company match, in a pass where a known-lettered company came back positive, so the clean result is real and not a broken query. And note what follows from the correction: we only owe you the Belmar sentence because RxSpan names its pharmacies. While this page was claiming it named nobody, there was nothing for a reader to check — which is a small illustration of why a false negative is not the safe direction to be wrong in.

Why that is not a formality: 503A compounders are state-licensed and specifically not subject to current good manufacturing practice requirements, while 503B outsourcing facilities register with FDA and must comply with them. Compounded drugs of either class are not FDA-approved¹ — and a buyer cannot look up a facility RxSpan will not name.

The evidence behind what it sells

RxSpan's own copy is restrained — it sells "healthspan" rather than reversal — but the molecules are the same ones the other providers here oversells, and the trial record is what it is.

On NAD+: the 2026 PRISMA-guided systematic review screened 113 studies including 33 human intervention trials, found effects on functional, metabolic and vascular outcomes "heterogeneous and often null or endpoint-specific" with clinical effectiveness "inconclusive," and reported that no eligible outcomes trial has evaluated intravenous or intramuscular NAD+ for anti-aging or wellness indications². That bears directly on the $249 injection tier, and on any bioavailability argument for it over the $199 tablet. A 2025 meta-analysis in adults averaging over 60 found NMN and NR did not improve muscle index, grip strength, gait speed or chair-stand time³.

On sermorelin: the trial of that exact molecule — GHRH 1-29, given nightly for six weeks to eleven healthy men aged 64–76 with low baseline IGF-1 — raised nocturnal growth hormone significantly while producing no change in IGF-1 and no change in DEXA-measured muscle or fat⁴. The landmark systematic review of growth hormone in healthy older adults found small body-composition shifts, no proven functional benefit and significantly more adverse events⁵. See NAD+ for longevity, peptides for longevity and what's proven versus hyped.

Where it's weak, and who should skip it

Skip it if you need to know what kind of facility compounds your medication — RxSpan names the four candidates but classifies none of them, and never says which one fills your particular order. Skip it if paying before assessment with no published refund policy is a risk you will not take. And skip it if $249 is simply too much: it sits near the best options here's month-to-month range for NAD+, and two A-graded competitors sit well below it.

If you proceed, choose the Monthly plan deliberately rather than accepting the $597 default, and ask two questions in writing first: which of the four named pharmacies fills your prescription and under what compounding standard, and what happens to your money if the provider declines you.

The verdict, against the rubric

Our rubric scores five things out of fourteen: price transparency (4), a genuine longevity line (4), clinical oversight (2), pharmacy disclosure (2) and human support (2). RxSpan MD takes price transparency in full — one all-inclusive figure per product with the plan ladder shown, which is more than most providers here manage — plus four for a real longevity line, two for a consult inside the price, and two for unlimited clinician access. It takes one of two on pharmacy — it names four dispensing facilities with phone numbers, which is the middle rung, but states no compounding standard for any of them, which is the top one. Thirteen of fourteen. An A.

The letter is right and the shape of it is unusual: this is among the most disclosure-forward rows we grade — founder, clinicians, NPIs and four pharmacies — and it still will not say what kind of pharmacy any of them is. State a compounding standard for the four it already names and it would be a fourteen tomorrow, without changing a single price. The full graded field is at our provider rankings; its neighbors are our Direct Meds review and Enhance MD review.