PhenoAge (phenotypic age) is a published measure of biological age developed by Morgan Levine and colleagues in 2018. It combines nine routine clinical blood biomarkers and your chronological age into a single 'age-equivalent' number, trained on NHANES mortality data. A PhenoAge below your real age suggests biologically younger physiology; above it suggests the opposite.

Which blood tests do I need?

You need a standard chemistry panel and a complete blood count (CBC) with differential — both routine and inexpensive. Specifically: albumin, creatinine, fasting glucose, C-reactive protein (CRP), lymphocyte percent, mean cell volume (MCV), red cell distribution width (RDW), alkaline phosphatase (ALP), and white blood cell count (WBC).

What units should I use?

The equation is calibrated to specific units (albumin g/L, creatinine µmol/L, glucose mmol/L, CRP mg/dL, and so on). To avoid mistakes, each field has a toggle so you can enter values in either conventional US units or SI units — the calculator converts them for you before applying the formula.

Is this the same as an epigenetic clock?

No. PhenoAge here is computed from blood biomarkers, not DNA methylation. Levine's group later trained an epigenetic 'DNAm PhenoAge' clock, but this tool uses the original blood-based phenotypic-age equation, which anyone with a standard lab panel can compute.

Is this medical advice?

No. This is an educational estimate using a published research equation. It is not a diagnosis, not a mortality prediction for you as an individual, and not a substitute for a clinician interpreting your labs in context.

Interactive tool · Biological age

Biological Age Calculator

Most “bio-age” quizzes are vibes. This one isn't: it runs the exact published Levine PhenoAge equation (Levine et al., 2018) over nine routine blood biomarkers and your age, and returns your phenotypic age — a peer-reviewed, mortality-trained measure of biological aging you can compute from a standard lab panel. Enter your numbers in conventional or SI units; the math runs in your browser and shows its working.

Read before you use this

This is an educational research calculator, not a medical assessment. PhenoAge is a population model: it estimates biological aging from group-level mortality data and is not a personal mortality prediction. A single panel is a snapshot — acute illness, infection, dehydration, recent exercise, or a lab error can swing CRP, WBC and glucose and distort the result. Biological age is one of many signals, not a verdict. Always have a licensed clinician interpret your bloodwork in the context of your full health history, and never start, stop, or change treatment based on a number from this tool.

Which model this is — in plain terms

Unlike our fitness-age tool, this is not a heuristic — PhenoAge is a published, public clinical equation, so we implement it verbatim. We use the paper's exact coefficients and the exact two-step conversion (a weighted linear score, then a Gompertz mortality transform into an age-equivalent), and we verified our implementation against a known worked example before shipping: a mid-normal 40-year-old's panel returns a PhenoAge of about 30.9 years, as the literature expects. The only thing we add is unit handling — the coefficients are calibrated to specific units (albumin g/L, creatinine µmol/L, glucose mmol/L, CRP mg/dL), and the per-field toggles convert your conventional or SI values to those before the formula runs. Honesty over false precision: where the source is a real published equation, we use it exactly; where it isn't, we say so.

Chronological ageyrYour actual age in years (18–100).AlbuminA blood protein. US labs report g/dL (e.g. 4.7); SI is g/L (×10).CreatinineA kidney-function marker. US mg/dL (e.g. 0.8); SI µmol/L (×88.4).Fasting glucoseBlood sugar. US mg/dL (e.g. 99); SI mmol/L (÷18).C-reactive protein (CRP)An inflammation marker. Most US labs report mg/L (e.g. 1.0). Must be above 0.Lymphocyte percent%Lymphocytes as a % of white cells (from a CBC with differential).Mean cell volume (MCV)fLAverage red-blood-cell size, in fL.Red cell distribution width (RDW)%Variation in red-cell size, as a % (from a CBC).Alkaline phosphatase (ALP)U/LA liver/bone enzyme, in U/L (= IU/L).White blood cell count (WBC)10³/µLIn 10³ cells/µL — e.g. enter 5.0 for 5,000/µL.

Your PhenoAge (biological age)

30.9yr

Your blood-biomarker biological age is younger than your chronological age — about 9.1 years younger.

Vs. chronological age

−9.1yr

Compared with your stated age of 40. A negative number means biologically younger; positive means older. This is roughly “PhenoAgeAccel” in the literature.

PhenoAge: 30.9 yr; Levine phenotypic age
Linear score (xb): -10.059; weighted biomarker sum
10-yr mortality score: 0.8400000000000001%; model-implied, not a forecast

How it is calculated. This is the exact published Levine PhenoAge equation (Levine et al., 2018) — a weighted sum of nine routine blood biomarkers plus your age, converted through a Gompertz mortality model into an “age-equivalent.” We apply the paper's coefficients verbatim, in the units the equation requires (albumin g/L, creatinine µmol/L, glucose mmol/L, CRP mg/dL as ln, lymphocyte %, MCV fL, RDW %, ALP U/L, WBC 10³/µL); your inputs are converted to those units first. Worked example: albumin 47 g/L, creatinine 71 µmol/L, glucose 5.5 mmol/L, CRP 0.1 mg/dL, lymphocyte 33%, MCV 90 fL, RDW 13%, ALP 50 U/L, WBC 5.0, age 40 → PhenoAge 30.9 years (a mid-normal 40-year-old reads biologically younger). All arithmetic runs in your browser — nothing is sent anywhere.

Questions, answered

What is PhenoAge?: PhenoAge (phenotypic age) is a published measure of biological age developed by Morgan Levine and colleagues in 2018. It combines nine routine clinical blood biomarkers and your chronological age into a single 'age-equivalent' number, trained on NHANES mortality data. A PhenoAge below your real age suggests biologically younger physiology; above it suggests the opposite.
Which blood tests do I need?: You need a standard chemistry panel and a complete blood count (CBC) with differential — both routine and inexpensive. Specifically: albumin, creatinine, fasting glucose, C-reactive protein (CRP), lymphocyte percent, mean cell volume (MCV), red cell distribution width (RDW), alkaline phosphatase (ALP), and white blood cell count (WBC).
What units should I use?: The equation is calibrated to specific units (albumin g/L, creatinine µmol/L, glucose mmol/L, CRP mg/dL, and so on). To avoid mistakes, each field has a toggle so you can enter values in either conventional US units or SI units — the calculator converts them for you before applying the formula.
Is this the same as an epigenetic clock?: No. PhenoAge here is computed from blood biomarkers, not DNA methylation. Levine's group later trained an epigenetic 'DNAm PhenoAge' clock, but this tool uses the original blood-based phenotypic-age equation, which anyone with a standard lab panel can compute.
Is this medical advice?: No. This is an educational estimate using a published research equation. It is not a diagnosis, not a mortality prediction for you as an individual, and not a substitute for a clinician interpreting your labs in context.

Put the number in context

A bio-age number is only useful if you know what drives it and how it compares to the other ways of measuring aging:

Reference

Levine ME, Lu AT, Quach A, Chen BH, Assimes TL, Bandinelli S, et al. An epigenetic biomarker of aging for lifespan and healthspan. Aging (Albany NY). 2018 Apr 18;10(4):573–591. PMID 29676998. This calculator implements the paper's blood-based phenotypic-age (PhenoAge) equation exactly, with unit conversion to the formula's required units.

This calculator is informational and not medical advice. It applies a published research equation to lab values you enter and does not account for your individual health history, medications, acute illness, or lab-method differences. It is not a diagnosis and not a personal mortality prediction. Consult a licensed clinician to interpret your bloodwork and before making any health decisions.